Boston University has discovered a new biomarker (CCL11) which can diagnose CTE (Chronic Traumatic Encephalopathy). For the first time, studies have revealed that this protein can diagnose the chronic brain disease.
Boston University research has shown that CTE signs were found in 110 out of 111 deceased National Football League Players.
For this research, Boston university researchers have studied the brains of 23 former professional and college football players and compared these brains with 18 non-athlete controls and 50 non-athletes suffering from Alzheimer’s disease.
This research has shown that CCL11 levels were common amongst the non-athlete (non-controls and Alzheimer’s disease). Researchers have taken the post-mortem sample of four control individuals, 4 individuals with Alzheimer’s disease and seven individuals with CTE.
This study has shown that CCL11 levels were elevated in the individuals with CTE, whereas it was low in the individuals with Alzheimer’s disease and control. So, they have drawn a conclusion that presence of CCL11 in the cerebrospinal Fluid can help to detect the CTE during the life of an individual.
Dr. Jonathan Cherry explained that this study has helped them to distinguish amongst the individuals with control and individuals with Alzheimer’s disease and CTE. This would help them to provide more targeted and effective therapies to individuals with CTE.
Authors of this study also said that CCL11 could be used as a combination with other procedures and biomarkers, such as PET scans to diagnose the CTE in living. Individuals with repetitive brain trauma and athletes are more inclined to get affected with CTE, said the researchers.